Contents
OMEPRAZOLE TABLETS 10mg"TOWA" are acid secretion suppressants. They strongly reduce gastric acid secretion and mitigate its harmful effects. As a result, they promote healing of gastric ulcers and gastroesophageal reflux disease (GERD) and relieve stomach pain and heartburn. They are also effective for gastric ulcers caused by aspirin or nonsteroidal anti‑inflammatory drugs (NSAIDs).
 
In addition, OMEPRAL is used in combination with two antibiotics for eradication of Helicobacter pylori, the bacterium responsible for various gastric lesions including gastritis and peptic ulcers. Reducing gastric acid enhances antibiotic effectiveness in the stomach and increases eradication success rates.
 
*OMEPRAZOLE TABLETS 10 mg "TOWA" is a generic version of OMEPRAL Tablets.

Efficacy
OMEPRAZOLE TABLETS 10 mg "TOWA" suppress gastric acid secretion by inhibiting the proton pump enzyme involved in the final step of acid production.
It is commonly used to treat gastric ulcers, duodenal ulcers, anastomotic ulcers, gastroesophageal reflux disease (GERD), non‑erosive reflux disease, and Zollinger–Ellison syndrome.
 
It is also used with two other antimicrobial agents as part of Helicobacter pylori eradication therapy and in treatments related to gastric ulcers, duodenal ulcers, gastric MALT lymphoma, immune thrombocytopenia, and post‑endoscopic therapy for early gastric cancer.
 

Usage
[Gastric ulcer, duodenal ulcer, anastomotic ulcer, Zollinger–Ellison syndrome]:
Usual adult dose: 2 tablets (20 mg as the active ingredient) once daily. Duration: up to 8 weeks for gastric and anastomotic ulcers; up to 6 weeks for duodenal ulcers.
 
[Gastroesophageal reflux disease (GERD)]:
Usual adult dose: 2 tablets (20 mg) once daily. Duration: up to 8 weeks. For recurrent GERD, maintenance dose: 1–2 tablets (10–20 mg) once daily.
 
[Non‑erosive gastroesophageal reflux disease (NERD)]:
Usual adult dose: 1 tablet (10 mg) once daily. Duration: up to 4 weeks.
 
[Adjunctive therapy for Helicobacter pylori eradication]:
Usual regimen: 2 tablets (20 mg) plus amoxicillin hydrate 750 mg and clarithromycin 200 mg, all taken together twice daily for 7 days. Clarithromycin may be increased if needed up to 400 mg twice daily.
If eradication fails: 2 tablets (20 mg) plus amoxicillin hydrate 750 mg and metronidazole 250 mg, all taken together twice daily for 7 days.
Always follow the prescribed administration instructions.
 
 
Do not chew or crush — these are enteric‑coated tablets.
If you miss a dose, take it as soon as you remember. If the next scheduled dose is near, skip the missed dose and take only the next scheduled dose. Do not take two doses at once.
If an overdose is suspected, consult a physician or pharmacist.
Do not discontinue treatment without your physician’s instruction.

Internal capacity
10mg x 100 tablets
10mg x 500 tablets
 
 
＜Warning＞
History of allergic reactions (e.g., itching, rash) to any drugs or foods.
Pregnancy or breastfeeding.
Concurrent use of other medications or products (including OTC medicines and foods) — these may increase or decrease the effects of this drug; exercise caution and inform your healthcare provider.
 
The main adverse reactions reported include hepatic dysfunction; diarrhea/soft stools; constipation; leukopenia (symptoms: sore throat, fever, oral ulcers); anemia; taste disturbances; rash, urticaria, itching; erythema multiforme; and photosensitivity. If you notice any of these symptoms, consult your physician or pharmacist.
 
Rarely, the following symptoms may occur and could be early signs of the adverse reactions shown in brackets. If you experience any of these, discontinue use and seek immediate medical attention.
 
Difficulty breathing, urticaria, swelling of the face, lips, or tongue [shock, anaphylaxis]
General fatigue, fever, nosebleeds or subcutaneous bleeding [pancytopenia, agranulocytosis, hemolytic anemia, thrombocytopenia]
Nausea or vomiting, loss of appetite, yellowing of the skin or eyes [fulminant hepatitis, hepatic dysfunction, jaundice, liver failure]
Fever, general malaise, rash or redness on the skin, eyes, or in the mouth [Stevens–Johnson syndrome, toxic epidermal necrolysis]
Fever, cough, shortness of breath [interstitial pneumonia]

These lists are not exhaustive. If you experience any other concerning symptoms, consult your physician or pharmacist.

Ingredients 
[Active ingredient]
Per tablet:
JP Pharm. omeprazole 10 mg
 
[Excipients]
lactose monohydrate, sodium lauryl sulfate, hydroxypropylcellulose, low‑substituted hydroxypropylcellulose, magnesium hydroxide, magnesium stearate, hypromellose phthalate, synthetic hydrotalcite, talc, titanium dioxide, cetanol, polyvinyl alcohol (partially saponified), macrogol 6000, and one other ingredient.