Contents
OMEPRAL Tablets 10 are acid secretion suppressants.
They strongly reduce gastric acid secretion and mitigate its harmful effects. As a result, they promote healing of gastric ulcers and gastroesophageal reflux disease (GERD) and relieve stomach pain and heartburn. They are also effective for gastric ulcers caused by aspirin or nonsteroidal anti‑inflammatory drugs (NSAIDs).
 
In addition, OMEPRAL is used in combination with two antibiotics for eradication of Helicobacter pylori, the bacterium responsible for various gastric lesions including gastritis and peptic ulcers. Reducing gastric acid enhances antibiotic effectiveness in the stomach and increases eradication success rates.
 
Efficacy
Acts on the proton pump, the final step of gastric acid secretion, thereby suppressing acid production.
 
Commonly used to treat gastric ulcers, anastomotic ulcers, duodenal ulcers, gastroesophageal reflux disease (GERD), non‑erosive reflux disease, and Zollinger–Ellison syndrome, and for maintenance therapy to prevent GERD recurrence.
 
It is also used with two other antibiotics as part of Helicobacter pylori eradication therapy and in treatment related to gastric ulcers, duodenal ulcers, gastric MALT lymphoma, idiopathic thrombocytopenic purpura, and post‑endoscopic treatment for early gastric cancer.
 

Usage
[Gastric ulcer, anastomotic ulcer, duodenal ulcer, Zollinger–Ellison syndrome, gastroesophageal reflux disease (GERD)]:
Usual adult dose: 2 tablets (20 mg as the active ingredient) once daily. Duration: up to 8 weeks for gastric and anastomotic ulcers and GERD; up to 6 weeks for duodenal ulcers. Follow prescribed instructions.
 
[Non‑erosive gastroesophageal reflux disease (NERD)]:
Usual adult dose: 1 tablet (10 mg) once daily. Duration: up to 4 weeks. Follow prescribed instructions.
 
[Maintenance therapy for recurrent GERD]:
Usual adult dose: 1–2 tablets (10–20 mg) once daily. Follow prescribed instructions.
 
[Helicobacter pylori eradication]:
First‑line regimen: Usual adult dose: 2 tablets (20 mg) plus amoxicillin hydrate 750 mg and clarithromycin 200 mg or 400 mg, all taken together twice daily.
If the above regimen fails: Usual adult dose: 2 tablets (20 mg) plus amoxicillin hydrate 750 mg and metronidazole 250 mg, all taken together twice daily.
Follow prescribed instructions.
 
Do not chew or crush — these are enteric‑coated tablets.
If you miss a dose, take it as soon as you remember. If the next scheduled dose is near, skip the missed dose and take only the next scheduled dose. Do not take two doses at once.
If an overdose is suspected, consult a physician or pharmacist.
Do not discontinue treatment without your physician’s instruction.

Internal capacity
10mg x 100 tablets
10mg x 500 tablets
 
＜Warning＞
History of allergic reactions (e.g., itching, rash) to any drugs or foods.
Pregnancy or breastfeeding.
Concurrent use of other medications or products (including OTC medicines and foods) — these may increase or decrease the effects of this drug; exercise caution and inform your healthcare provider.
 
 
The main adverse reactions reported include hepatic dysfunction, diarrhea/soft stools, leukopenia (symptoms: sore throat, fever, oral ulcers), taste disturbances, and hypersensitivity reactions such as rash and itching. If you notice any of these symptoms, consult your physician or pharmacist.
 
Rarely, the following symptoms may occur and could be early signs of the adverse reactions shown in brackets. If you experience any of these, discontinue use and seek immediate medical attention.
 
Difficulty breathing, urticaria, swelling of the face, lips, or tongue [shock, anaphylaxis]
General fatigue, fever, nosebleeds or subcutaneous bleeding [pancytopenia, agranulocytosis, hemolytic anemia, thrombocytopenia]
Nausea or vomiting, loss of appetite, yellowing of the skin or eyes [fulminant hepatitis, hepatic dysfunction, jaundice, liver failure]
Fever, general malaise, rash or redness on the skin, eyes, or in the mouth [Stevens–Johnson syndrome, toxic epidermal necrolysis]
Fever, cough, shortness of breath [interstitial pneumonia]

These lists are not exhaustive. If you experience any other concerning symptoms, consult your physician or pharmacist.

Ingredients 
[Active ingredient]
Per tablet:
JP Pharm. omeprazole 10 mg
 
[Excipients]
Lactose monohydrate, sodium starch glycolate, hydroxypropylcellulose, sodium lauryl sulfate, magnesium hydroxide, magnesium stearate, hypromellose, synthetic hydrotalcite, titanium dioxide, hypromellose phthalate, cetanol, talc, carnauba wax.