Contents
RABEPRAZOLE Na Tablets[SAWAI] 10 mg are an acid secretion suppressant. They potently reduce gastric acid secretion and mitigate its harmful effects. As a result, they promote healing of gastric ulcers and gastroesophageal reflux disease (GERD) and relieve stomach pain and heartburn. They are also effective for gastric ulcers caused by aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs).
 
In addition, they are used as part of eradication therapy for Helicobacter pylori, the bacterium responsible for various gastric lesions including gastritis and peptic ulcers. In this use, Pariet is combined with two other antibiotics; reducing gastric acid enhances the efficacy of the antibiotics and increases eradication success rates.
 
*RABEPRAZOLE Na Tablets [SAWAI] 10 mg is a generic version of Pariet tablets.

Efficacy
Suppresses gastric acid by inhibiting the proton pump, the final step of acid secretion.
Commonly used to treat gastric ulcers, duodenal ulcers, anastomotic ulcers, GERD, Zollinger–Ellison syndrome, and non‑erosive reflux disease; to prevent recurrence of gastric or duodenal ulcers during low‑dose aspirin therapy; and as adjunctive therapy for Helicobacter pylori eradication.
 

Usage
[Gastric ulcer, duodenal ulcer, postoperative anastomotic ulcer, Zollinger–Ellison syndrome]:
Usual adult dose: 10 mg (as the active ingredient) once daily. May be increased to 20 mg once daily depending on condition.
Duration: up to 8 weeks for gastric and anastomotic ulcers; up to 6 weeks for duodenal ulcers.
 
 
[Gastroesophageal reflux disease (GERD)]:
(Treatment): Usual adult dose: 10 mg once daily; may be increased to 20 mg once daily depending on condition. Duration: up to 8 weeks.
For GERD inadequately controlled with a proton pump inhibitor (PPI): 10 mg or 20 mg twice daily for an additional 8 weeks. The 20 mg twice‑daily regimen is reserved for severe mucosal injury.
(Maintenance therapy): For recurrent GERD, 10 mg once daily. For maintenance in GERD inadequately controlled by a PPI, 10 mg twice daily.
 
 
[Non‑erosive gastroesophageal reflux disease (NERD)]:
Usual adult dose: 10 mg once daily. Duration: up to 4 weeks.
 
 
]Prevention of recurrence of gastric or duodenal ulcers in patients receiving low‑dose aspirin]:
Usual adult dose: 5 mg once daily; if insufficient, 10 mg once daily.
 
 
[Adjunctive therapy for Helicobacter pylori eradication]:
Usual adult regimen: 10 mg twice daily concomitantly with amoxicillin hydrate and clarithromycin for 7 days. If eradication fails, 10 mg twice daily concomitantly with amoxicillin hydrate and metronidazole for 7 days.
 
Each tablet contains 10 mg of the active ingredient.
Always follow the prescribed administration method.
Swallow tablets whole; do not chew or crush.
If you miss a dose, take it as soon as you remember. If it is nearly time for the next dose, skip the missed dose and take the next scheduled dose. Do not take two doses at once.
If an overdose is suspected, consult a physician or pharmacist.
Do not discontinue treatment without your physician’s instruction.

Internal capacity
10mg x 100 tablets
 
＜Warning＞
History of allergic reactions (e.g., itching, rash) to any drugs or foods.
Presence of liver disorder.
Pregnancy or breastfeeding.
Concurrent use of other medications or products (including OTC medicines and foods) — these may increase or decrease the effects of this drug; please take care and inform your healthcare provider.
 
The main adverse reactions reported include rash, urticaria, pruritus, diarrhea, soft stools, taste disturbances, abdominal pain, abdominal bloating, and constipation. If you notice any of these symptoms, consult your physician or pharmacist.
Rarely, the following symptoms may occur and could represent early signs of the adverse reactions indicated in brackets. If you experience any of these, discontinue use and seek immediate medical attention.
 
 
Dizziness, dyspnea, and generalized itching with redness [shock, anaphylaxis]
General fatigue, fever, sore throat, bleeding tendency [pancytopenia, agranulocytosis, thrombocytopenia, hemolytic anemia]
General fatigue, loss of appetite, jaundice (yellowing of skin or whites of eyes) [fulminant hepatitis, hepatic dysfunction, jaundice]
Fever, cough, dyspnea [interstitial pneumonia]
Fever, painful swelling and blistering of skin/mucous membranes, conjunctival redness [Stevens–Johnson syndrome, toxic epidermal necrolysis, erythema multiforme]
Decreased urine output, swelling, fever [acute renal injury, interstitial nephritis]
Nausea/vomiting, seizures, headache, impaired consciousness [hyponatremia]
Muscle pain, weakness, dark red‑brown urine [rhabdomyolysis]
Decreased vision or visual field abnormalities [visual impairment]
Delirium, abnormal behavior, hallucinations [confusional state]
 
These lists are not exhaustive. If you experience any other worrying symptoms, consult your physician or pharmacist.
 

Ingredients 
[Active ingredient]
JP Pharm. rabeprazole sodium 10 mg
 
[Excipients]
carnauba wax, carmellose calcium, glycerol fatty acid esters, titanium dioxide, magnesium oxide, iron(III) oxide, magnesium stearate, talc, hydroxypropylcellulose, hypromellose phthalate, trehalose, macrogol 6000, dibasic calcium phosphate