TRANCOLON Tablets 7.5mg - irritable bowel syndrome (IBS) “Astellas” 
 
irritable bowel syndrome (IBS)
This disease is most likely to occur when you have abdominal pain or discomfort, and related bowel abnormalities such as constipation or diarrhea (abnormal bowel movements or stool shape) that persist for several months or more.
 
Contents 
Gastrointestinal motility is increased by commands from the parasympathetic nervous system. This medicine has the effect of weakening parasympathetic nerve stimulation (anticholinergic effect). As a result, gastrointestinal motility is suppressed, and abdominal pain and diarrhea symptoms associated with irritable bowel disease are improved. 
However, irritable bowel disease itself cannot be cured. It is a symptomatic drug that suppresses symptoms. 
 
Efficacy 
This medicine acts on the enteric nerves and controls abnormal intestinal movements. 
It is usually used to improve symptoms of irritable colon, including abdominal pain, repeated diarrhea and constipation, etc. 
 
Usage 
The usual adult dose of mepenzolate bromide is 15 mg (2 tablets) taken orally three times a day. The dosage may be increased or decreased as appropriate depending on age and symptoms. 
Internal capacity 
500 tablets 
 
＜Warning＞ 
● At the medical examination 
If you have any medical conditions or allergies, please tell your doctor. Symptoms may worsen depending on the disease. 
If you are taking any other medicines, please tell your doctor. 
  
● People to be careful about 
It is prohibited for people with angle-closure glaucoma. This is because intraocular pressure may rise and symptoms may worsen. It should also not be used by people who have difficulty urinating due to enlarged prostate or who have intestinal obstruction. Also avoid in cases of bacterial diarrhea such as hemorrhagic colitis. In addition, people with heart disease, ulcerative colitis, or hyperthyroidism should use this medicine with caution. 
  
Unsuitable case. ．． Angle-closure glaucoma, urinary dysfunction, severe heart disease, intestinal obstruction, paralytic ileus, bacterial diarrhea. 
A case that requires caution. ．． Open-angle glaucoma, enlarged prostate, heart disease, ulcerative colitis, hyperthyroidism, elderly people, people who work in hot places, etc. 
  
● Mixing drinks/meals 
The side effects of both drugs can be increased when used with certain tranquilizers or antidepressants. Be sure to inform your doctor if you are taking any other medications. 
  
Be careful about mixing drinks. ．． Stabilizers (phenothiazines, butyrophenones), antidepressants (tricyclics), cold medicines, rhinitis medicines, anti-itch medicines (antihistamines), etc. 
  
● For use 
The amount and method of drinking varies depending on your symptoms. Please drink exactly as directed. 
  
● life 
Objects may appear blurry or dazzling. Be careful when doing dangerous activities such as driving a car. 
Since sweating becomes difficult, there is a risk of heat stroke or heat stroke. Be careful of working in hot places, strenuous exercise, and the summer heat. 
 
The most common side effects include dry mouth, constipation, difficulty urinating, and blurred vision. Although it rarely becomes serious, if your symptoms are severe, please seek medical attention as soon as possible. Elderly men especially need to be careful about urinary problems. 
 
Ingredients  
Active ingredient：Mepenzolate bromide 
 
Dosage form：pale reddish white tablet, diameter: approx. 6.1 mm, thickness: approx. 2.9 mm