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Paste medicine LOQOA tapes Taisho Pharmaceutical(Introducing a new pain reliever)

Front view of Loqoa Tape in a bag

If other painkillers don't work for you, you may want to try it.

What is LOQOA tapes?

LOQOA tapes is new pain medication in Effective in relieving joint pain and inflammation.

This patch belongs to a group called transdermal analgesics and inflammatory agents (non-steroidal anti-inflammatory analgesics), and the active ingredients are esflurbiprofen and peppermint oil.

It is classified as NSAIDs (non-steroidal anti-inflammatory drugs), the same as ``Loxonin'' and ``Ibuprofen'', which are often heard as painkillers.

LOQOA tapes is Developed so that the drug is absorbed and is more effective than conventional was done.

The reason why it is called ``patch medicine'' is because although it is a patch medicine, it has properties similar to oral medicine.

How easy is the active ingredient in LOQOA tapes to be absorbed? LOQOA tapes The drug concentration in the blood when two sheets of the drug are applied reaches the same level as when the drug is continued to be taken orally. It has been reported that.

In addition, it disappears from the body relatively quickly, and rapid recovery can be expected by removing the drug when side effects occur.

In February 2020, we made some changes to the formulation with the aim of improving ease of removal after use while maintaining resistance to peeling during application.


Analgesic/anti-inflammatory in osteoarthritis

Pharmacological action

LOQOA tapes S-flurbiprofen, the active ingredient in , has the effect of inhibiting the action of an enzyme called cyclooxygenase (COX), which acts on the production of prostaglandins that cause inflammation. Prostaglandin, which is the cause of inflammation and pain, is no longer produced, resulting in a reduction in inflammation and an analgesic effect.


・Apply to the affected area once a day. Do not attach more than two sheets at the same time.

・Maximum number of stickers per day is 2.

・As a general rule, avoid concomitant use with oral painkillers (oral NSAIDs).

side effect

When using it, the same caution as with oral NSAIDs is required. Pay attention to symptoms to see if there are any gastrointestinal disorders as a side effect.

If you experience any symptoms such as heaviness in your stomach, stomach pain, heartburn, nausea, dark stools, or blood in your stools, discontinue use and seek medical attention.

We will introduce some serious side effects that you should be especially careful about.



・Acute renal insufficiency

・Nephrotic syndrome

・Gastrointestinal bleeding

・Aplastic anemia

・Induction of asthma attacks (aspirin asthma)

・Toxic epidermal necrolysis (TEN)

・Oculomucocutaneous syndrome (Stevens-Johnson syndrome)

・Exfoliative dermatitis

・Consciousness disorder

・Convulsions accompanied by loss of consciousness

If you experience these symptoms,Discontinue use and seek medical advice immediately.

Precautions for use

Use up to 2 pieces per day (even if there are multiple painful areas)

LOQOA tapes the absorption rate of the drug is good, so if you apply a lot of it at once, it will have the same effect on your body as if you took a large amount of oral medicine. Therefore, the number of sheets that can be used per day is limited. A maximum of 2 items can be used per day.

In principle, avoid concomitant use with other anti-inflammatory analgesics.

LOQOA tapes the drug has a high absorption rate and is absorbed into the body to the same extent as oral medication, so if used in conjunction with other painkillers (oral medication, patch), there is a high possibility of side effects occurring.

If you are using over-the-counter non-steroidal anti-inflammatory drugs (such as Loxonin, Bufferin, Voltaren, etc.), be sure to consult your doctor.

In addition to painkillers, it has been reported that convulsions may occur when used in combination with quinolone antibiotics.

In addition, there is a possibility of interactions with anticoagulant warfarin, antirheumatic drugs (Rheumatrex, etc.), tranquilizers, diuretics, etc., so be careful when taking this drug with other drugs.

If you are about to start using LOQOA tapes, please be sure to tell your doctor or pharmacist about the medications you are currently using.

If you are already using LOQOA tapes and want to start using another medicine, be sure to consult your doctor or pharmacist.

What to do in case of skin problems

LOQOA tapes Skin problems are a relatively common side effect.

If any skin symptoms (such as eczema, redness, or peeling of the skin) occur during use, discontinue use and consult your doctor or pharmacist.

What to do if you forget to use it

Please apply it as soon as you notice that you forgot to apply it.

LOQOA tapes people who cannot use

If you have ever had hypersensitivity to brolobiprofen or LOQOA tapes.

People with hypersensitivity should be careful when using this product, as its use may cause allergic symptoms and, in the worst case, allergic shock. If you have never used this product before, if you experience any signs of allergic reaction such as cold sweats, pale face, decreased blood pressure, dizziness, difficulty breathing, hives, or discomfort, immediately stop using the product and seek medical attention.

Those who are being treated for gastrointestinal ulcers such as gastric ulcers

LOQOA tapes Prostaglandin, whose action is suppressed by its medicinal properties, also has the function of suppressing gastric acid secretion and protecting the gastric mucosa. By suppressing these functions when using LOQOA tapes, the protective effect on the gastric mucosa may be lost, leading to the occurrence or worsening of gastritis and gastric ulcers.

Those who have ever had asthma caused by analgesics or antipyretics (those with aspiric asthma)

Please be careful as it may induce an asthma attack.

Women in late pregnancy (after 28 weeks of pregnancy) and breastfeeding women

LOQOA tapes However, there have been reports that fetal arterial constriction occurred when other non-steroidal anti-inflammatory drug patches were used in the third trimester, so they cannot be used in the third trimester. Safety for use during pregnancy has not been established and should only be used when the risks outweigh the benefits of treatment. Experiments on rats have confirmed that it passes into breast milk, so avoid using it while breastfeeding. If it is unavoidable to use the product while breastfeeding, please stop breastfeeding during and after use.

Those with severe liver, kidney, or heart function decline or high blood pressure

Side effects may worsen the condition of people with impaired liver, kidney, or heart function. Additionally, use of LOQOA tapes inhibits the function of prostaglandins, leading to retention of water and sodium in the body, which may further increase blood pressure, so in principle, it cannot be used by people with high blood pressure.

People with a tendency to bleed

It cannot be used as it may worsen blood abnormalities.

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