This drug reduces potassium in the blood. It is used when potassium is increased, such as in kidney failure.

When the kidneys are not functioning properly, they are unable to excrete potassium adequately. As a result, potassium in the blood increases, causing symptoms such as shortness of breath, numbness in the hands and feet, anxiety, and in some cases, arrhythmia, which can be dangerous.

This medication adsorbs potassium in the intestines and excretes it with stool. Since potassium absorption is suppressed, the amount of potassium in the blood decreases. It is mainly used to treat hyperkalemia due to renal failure.

Characteristics

A type of ion exchange resin. It adsorbs potassium and at the same time releases calcium, leaving it in the body. Sodium polystyrene sulfone (Keixalate), a similar drug, releases sodium and leaves it in the body.

In addition to the powder form, granules, dry syrup, liquid and jelly formulations are also available.

Caution.

[On medical examination].

People with pre-existing medical conditions or allergies should inform their doctors. People who are prone to constipation should also report this.

If you are taking separate medication, tell your doctor.

[Persons to be wary of

This medicine has a tendency to cause constipation. People with gastrointestinal problems or who are prone to constipation should consult their doctor. Elderly people should also be careful about constipation.

It should also be used with caution in people with hyperparathyroidism or multiple myeloma. This is because the drug may increase calcium levels in the blood.

Unsuitable Cases . People with intestinal obstruction.

Cases requiring caution ... Constipation, intestinal stricture, gastrointestinal ulcer, hyperparathyroidism, multiple myeloma, etc.

Combination of taking and eating.

When used in combination with digitalis (digitalin, digoxin), a cardiotonic drug, be aware of digitalis toxicity. When potassium levels drop due to the action of these drugs, side effects caused by digitalis toxicity, such as arrhythmia, are more likely to occur.

If taken at the same time as a gastrointestinal drug containing aluminum or magnesium, the action of this drug may be weakened. Depending on the doctor's instructions, it may be advisable to stagger the time of taking this medicine.

Thyradin may reduce the effect of thyroid hormone preparations (thyradin). Consideration should be given to the time between doses.

When taken with drugs that cause constipation, side effects of constipation are more likely to occur. For example, codeine, a cough medicine, tricyclic antidepressants, anticholinergics used for Parkinson's disease and diarrhea.

When to use

The dosage depends on the symptoms. The dosage depends on the symptoms. Dosage and administration should be as directed by a physician. In general, one dose of powdered medicine should be mixed with 30-50 mL of water and swallowed.

If you have difficulty taking it, consult your doctor. In addition to jelly formulations that can be taken as is, apple- or orange-flavored liquid formulations are also available.

In some cases, it is injected directly into the intestine through the anus.

In some cases, a sorbitol solution (a type of sugar) is taken together with the jelly to prevent constipation.

Examination

Periodic checkups are required to monitor the effects and side effects of the medication. It is necessary to check that potassium and calcium levels are maintained properly.

Dietary habits

Make sure to defecate daily.

General usage

Dispersible formulation (general)

Oral: [Oral] (1) Calcium polystyrenesulfonate The usual adult dosage of calcium polystyrene sulfonate is 15 to 30 g two to three times a day, and each dose is suspended in 30 to 50 mL of water. Dosage may be adjusted according to symptoms.

Intravenous administration The usual adult dosage is 30 g per dose suspended in 100 mL of water or 2% methylcellulose solution and administered intravenously. The suspension should be warmed to body temperature and left in the intestinal tract for 30 minutes to 1 hour. If fluid leaks out, fist the patient on the buttocks with a pillow, or keep the patient in the kneecap position for a while. A 5% dextrose solution may be used in place of water or 2% methylcellulose solution.

Dosage and Administration 96.7%].

The usual adult dosage is 15.51-31.02 g (3-6 packets of this product: 15-30 g as calcium polystyrenesulfonate) two to three times a day, and each dose should be taken orally with 30 to 50 mL of water. Dosage may be adjusted according to symptoms.

Granules 89.29%]

The usual adult dosage is 16.80-33.60 g (15-30 g calcium polystyrenesulfonate) two to three times a day, each time taken orally with 30 to 50 mL of water. The dosage may be adjusted according to symptoms.

Dry Syrup 92.59%].

The usual adult dosage is 16.2 to 32.4 g (15 to 30 g of calcium polystyrenesulfonate daily) divided into two to three doses, each dose suspended in 30 to 50 mL of water, and taken orally. The dosage may be increased or decreased according to symptoms.

Oral solution 20%]

The usual adult dosage is 75 to 150 g (15 to 30 g of calcium polystyrenesulfonate per day) taken orally in two to three divided doses. The dosage may be adjusted according to symptoms.

Jelly 20%]

The usual adult dosage is 75 to 150 g (15 to 30 g of calcium polystyrenesulfonate per day) taken two to three times a day. Dosage may be adjusted according to symptoms.

Side Effects

Constipation is more common. If constipation persists, potassium is not excreted and the effect is weakened. In rare cases, constipation may become severe. If constipation is frequent, see your doctor as soon as possible.

If the medication is too effective, the body's potassium level may be lower than necessary, resulting in hypokalemia. Conversely, calcium levels may increase, causing hypercalcemia.

Severe side effects] . (Although rarely seen, please note the initial symptoms, etc., just in case.

Intestinal perforation, intestinal obstruction, colorectal ulcer Severe abdominal pain, persistent abdominal pain, vomiting, severe constipation, bloating, and bleeding.

Other]

Hypokalemia. Lethargy, muscle weakness (lack of strength), constipation, palpitations, irregular pulse.

Hypercalcemia Drowsiness, weakness, anorexia, nausea, vomiting, dry mouth, abdominal pain, headache, dizziness, irritability, itching, muscle weakness, myalgia.

Constipation, nausea, anorexia, diarrhea.