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List of drugs for treating upper gastrointestinal tract diseases


We have summarized the main ingredients and characteristics.


a: Gastric acid secretion suppressant

1) Proton pump inhibitors (PPIs)

Characteristics: Strong acid secretion suppressing effect, aids in Helicobacter pylori eradication, and first choice drug for reflux esophagitis.

Omeprazole,lansoprazol,rabeprazole,esomeprazole


2) Potassium ion competitive acid blocker (P-CAB)

Vonoprazan


3) Histamine (H2) receptor antagonists

Characteristics: Acid secretion inhibitor

Famotidine,cimetidine,roxatidine,nizatidine,lafutidine



4) Selective muscarinic receptor antagonist

Characteristics: Acid secretion inhibitor

Pirenzepine,tiquizium


5) Anticholinergic drugs

Characteristics: Parasympatholytic agent. Do not use in patients with benign prostatic hyperplasia, glaucoma, or heart disease.

piperidolate,scopolamine,timepidium,propantheline,N-methylscopolamine,atropine

merchandise:BUSCOPAN Tablets 10mg


6) Antacids

Features: Immediate effect.

sodium bicarbonate,precipitated calcium carbonate,dried aluminum hydroxide gel,magnesium hydroxide



b:Defensive factor enhancer

1) Prostaglandin preparations

Characteristics: Effective in preventing NSAIDS ulcers due to its mucosal protective action.

Misoprostol


2) Mucosal protective drug

Characteristics: Effective against erosions and ulcers due to mucosal protective action.

sucralfate,ecabet sodium hydrate,teprenone,rebamipide,methylmethionine,sodium gualenate hydrate,aldioxa,cetraxate,sofalcone,sodium alginate,troxipide,Benexate Hydrochloride Betadex,polaprezinc,irsogladine maleate,egualen sodium hydrate,


3) Tissue repair/mucus production secretion promoter


c:Gastrointestinal motility improving drug

1) Parasympathomimetic drugs (acetylcholinergic agonists)

Characteristics: Stimulates the sympathetic nervous system and promotes gastrointestinal motility and secretion of digestive juices.

Carnitine


2) Antidopamine drugs (dopamine receptor antagonists)

Characteristics: Antagonizes the binding of dopamine to D2 receptors, promotes the release of acetylcholine, and has antiemetic effects.

metoclopramide,domperidone,itopride hydrochloride

merchandise:GANATON Tablets 50mg


3) Opiate agonists

Characteristics: Acts on opioid receptors and regulates gastrointestinal motility.

Trimebutine


4) Selective serotonin receptor agonist

Characteristics: Stimulates serotonin receptors in the gastrointestinal tract and exhibits acetylcholinergic properties.

Mosapride





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